Nurse practitioner pay in Indianapolis, IN

Nurse practitioners in the Indianapolis-Carmel-Greenwood, IN metro area earn a typical $130,460 a year. The middle half earn $122,720 to $136,130, and the top 10% earn more than $152,090. About 2,530 people do this job there.

Source: BLS Occupational Employment and Wage Statistics, May 2025 (occupation: Nurse Practitioners, SOC 29-1171).

Typical pay$130,460
Take-home$7,830/mo
Worth in a typical US city$98,200
After cost of livingNo. 24 of 50

Pay range

Bottom 10% earn less than$106,500
25th percentile$122,720
Median (typical)$130,460
75th percentile$136,130
Top 10% earn more than$152,090

Typical pay here ranks No. 35 of 50 large metros for nurse practitioners before taxes and prices.

After taxes and cost of living

At the typical $130,460, a single filer keeps about $94,000 a year after federal, Social Security, Medicare, and Indiana state and local (about $2,635) income tax. Prices in Indianapolis are 4% below the US average, so that take-home buys what $98,200 would in a typical US city. That ranks Indianapolis No. 24 of 50 large metros for nurse practitioners after cost of living.

Where nurse practitioners’ pay goes furthest

  1. San Jose, CA$231,560 typical · worth $139k
  2. San Francisco, CA$219,080 typical · worth $127k
  3. Sacramento, CA$172,010 typical · worth $110k
  4. Las Vegas, NV$144,060 typical · worth $110k

All 50 metros for nurse practitioners →

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Common questions

How much does a nurse practitioner make in Indianapolis, IN?

The typical (median) nurse practitioner in the Indianapolis-Carmel-Greenwood, IN metro area earns $130,460 a year. The middle half earn between $122,720 and $136,130, and the top 10% earn more than $152,090. Source: BLS Occupational Employment and Wage Statistics, May 2025.

What is a good salary for a nurse practitioner in Indianapolis?

Anything above $130,460 pays more than half of nurse practitioners in Indianapolis. $136,130 or more puts you in the top quarter, and $152,090 in the top 10%. Experience and employer move where you should be in that range.

How much does a nurse practitioner in Indianapolis take home after taxes?

At the typical $130,460, a single filer keeps about $94,000 a year ($7,830 a month) after federal, Social Security, Medicare, Indiana state, and local income tax. With local prices 4% below the US average, that buys what $98,200 would in a typical US city.

Where do nurse practitioners get paid the most after cost of living?

Among the 50 largest US metros, typical nurse practitioner pay goes furthest after taxes and prices in San Jose, CA, San Francisco, CA, Sacramento, CA. Indianapolis, IN ranks No. 24.

More: Nurse practitioner pay in every large metro · Pay for other jobs in Indianapolis, IN

Local prices: BEA regional price parities, 2024. Updated November 2026.