Nurse practitioner pay in San Francisco, CA
Nurse practitioners in the San Francisco-Oakland-Fremont, CA metro area earn a typical $219,080 a year. The middle half earn $176,490 to $241,910, and the top 10% earn more than $273,960. About 3,110 people do this job there.
Source: BLS Occupational Employment and Wage Statistics, May 2025 (occupation: Nurse Practitioners, SOC 29-1171).
Pay range
| Bottom 10% earn less than | $153,280 |
| 25th percentile | $176,490 |
| Median (typical) | $219,080 |
| 75th percentile | $241,910 |
| Top 10% earn more than | $273,960 |
Typical pay here ranks No. 2 of 50 large metros for nurse practitioners before taxes and prices.
After taxes and cost of living
At the typical $219,080, a single filer keeps about $146,700 a year after federal, Social Security, Medicare, and California state income tax. Prices in San Francisco are 16% above the US average, so that take-home buys what $126,900 would in a typical US city. That ranks San Francisco No. 2 of 50 large metros for nurse practitioners after cost of living.
Where nurse practitioners’ pay goes furthest
- San Jose, CA$231,560 typical · worth $139k
- Sacramento, CA$172,010 typical · worth $110k
- Las Vegas, NV$144,060 typical · worth $110k
- Riverside, CA$169,920 typical · worth $109k
All 50 metros for nurse practitioners →
Where does your salary land?
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Common questions
How much does a nurse practitioner make in San Francisco, CA?
The typical (median) nurse practitioner in the San Francisco-Oakland-Fremont, CA metro area earns $219,080 a year. The middle half earn between $176,490 and $241,910, and the top 10% earn more than $273,960. Source: BLS Occupational Employment and Wage Statistics, May 2025.
What is a good salary for a nurse practitioner in San Francisco?
Anything above $219,080 pays more than half of nurse practitioners in San Francisco. $241,910 or more puts you in the top quarter, and $273,960 in the top 10%. Experience and employer move where you should be in that range.
How much does a nurse practitioner in San Francisco take home after taxes?
At the typical $219,080, a single filer keeps about $146,700 a year ($12,230 a month) after federal, Social Security, Medicare, California state income tax. With local prices 16% above the US average, that buys what $126,900 would in a typical US city.
Where do nurse practitioners get paid the most after cost of living?
Among the 50 largest US metros, typical nurse practitioner pay goes furthest after taxes and prices in San Jose, CA, Sacramento, CA, Las Vegas, NV. San Francisco, CA ranks No. 2.
More: Nurse practitioner pay in every large metro · Pay for other jobs in San Francisco, CA
Local prices: BEA regional price parities, 2024. Updated November 2026.