Nurse practitioner pay in Buffalo, NY
Nurse practitioners in the Buffalo-Cheektowaga, NY metro area earn a typical $132,220 a year. The middle half earn $111,890 to $150,400, and the top 10% earn more than $166,300. About 1,190 people do this job there.
Source: BLS Occupational Employment and Wage Statistics, May 2025 (occupation: Nurse Practitioners, SOC 29-1171).
Pay range
| Bottom 10% earn less than | $104,470 |
| 25th percentile | $111,890 |
| Median (typical) | $132,220 |
| 75th percentile | $150,400 |
| Top 10% earn more than | $166,300 |
Typical pay here ranks No. 25 of 50 large metros for nurse practitioners before taxes and prices.
After taxes and cost of living
At the typical $132,220, a single filer keeps about $94,900 a year after federal, Social Security, Medicare, and New York state income tax. Prices in Buffalo are 4% below the US average, so that take-home buys what $99,000 would in a typical US city. That ranks Buffalo No. 20 of 50 large metros for nurse practitioners after cost of living.
Where nurse practitioners’ pay goes furthest
- San Jose, CA$231,560 typical · worth $139k
- San Francisco, CA$219,080 typical · worth $127k
- Sacramento, CA$172,010 typical · worth $110k
- Las Vegas, NV$144,060 typical · worth $110k
All 50 metros for nurse practitioners →
Where does your salary land?
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Common questions
How much does a nurse practitioner make in Buffalo, NY?
The typical (median) nurse practitioner in the Buffalo-Cheektowaga, NY metro area earns $132,220 a year. The middle half earn between $111,890 and $150,400, and the top 10% earn more than $166,300. Source: BLS Occupational Employment and Wage Statistics, May 2025.
What is a good salary for a nurse practitioner in Buffalo?
Anything above $132,220 pays more than half of nurse practitioners in Buffalo. $150,400 or more puts you in the top quarter, and $166,300 in the top 10%. Experience and employer move where you should be in that range.
How much does a nurse practitioner in Buffalo take home after taxes?
At the typical $132,220, a single filer keeps about $94,900 a year ($7,910 a month) after federal, Social Security, Medicare, New York state income tax. With local prices 4% below the US average, that buys what $99,000 would in a typical US city.
Where do nurse practitioners get paid the most after cost of living?
Among the 50 largest US metros, typical nurse practitioner pay goes furthest after taxes and prices in San Jose, CA, San Francisco, CA, Sacramento, CA. Buffalo, NY ranks No. 20.
More: Nurse practitioner pay in every large metro · Pay for other jobs in Buffalo, NY
Local prices: BEA regional price parities, 2024. Updated November 2026.