Physician assistant pay in Buffalo, NY
Physician assistants in the Buffalo-Cheektowaga, NY metro area earn a typical $126,360 a year. The middle half earn $105,240 to $144,810, and the top 10% earn more than $160,880. About 1,040 people do this job there.
Source: BLS Occupational Employment and Wage Statistics, May 2025 (occupation: Physician Assistants, SOC 29-1071).
Pay range
| Bottom 10% earn less than | $98,820 |
| 25th percentile | $105,240 |
| Median (typical) | $126,360 |
| 75th percentile | $144,810 |
| Top 10% earn more than | $160,880 |
Typical pay here ranks No. 45 of 50 large metros for physician assistants before taxes and prices.
After taxes and cost of living
At the typical $126,360, a single filer keeps about $91,200 a year after federal, Social Security, Medicare, and New York state income tax. Prices in Buffalo are 4% below the US average, so that take-home buys what $95,200 would in a typical US city. That ranks Buffalo No. 35 of 50 large metros for physician assistants after cost of living.
Where physician assistants’ pay goes furthest
- San Jose, CA$223,640 typical · worth $135k
- Seattle, WA$167,290 typical · worth $113k
- San Antonio, TX$140,160 typical · worth $113k
- Oklahoma City, OK$138,920 typical · worth $111k
All 50 metros for physician assistants →
Where does your salary land?
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Common questions
How much does a physician assistant make in Buffalo, NY?
The typical (median) physician assistant in the Buffalo-Cheektowaga, NY metro area earns $126,360 a year. The middle half earn between $105,240 and $144,810, and the top 10% earn more than $160,880. Source: BLS Occupational Employment and Wage Statistics, May 2025.
What is a good salary for a physician assistant in Buffalo?
Anything above $126,360 pays more than half of physician assistants in Buffalo. $144,810 or more puts you in the top quarter, and $160,880 in the top 10%. Experience and employer move where you should be in that range.
How much does a physician assistant in Buffalo take home after taxes?
At the typical $126,360, a single filer keeps about $91,200 a year ($7,600 a month) after federal, Social Security, Medicare, New York state income tax. With local prices 4% below the US average, that buys what $95,200 would in a typical US city.
Where do physician assistants get paid the most after cost of living?
Among the 50 largest US metros, typical physician assistant pay goes furthest after taxes and prices in San Jose, CA, Seattle, WA, San Antonio, TX. Buffalo, NY ranks No. 35.
More: Physician assistant pay in every large metro · Pay for other jobs in Buffalo, NY
Local prices: BEA regional price parities, 2024. Updated November 2026.